Diclofenac: Use, Redirection and Side Effects
Diclofenac (INN) is a painkiller or non-steroidal anti-inflammatory drug (NSAID). Available under various names around the world. The name Diclofenac is derived from the chemical name: 2- (2,6-dichloranilino) phenylacetic acid. First brought to market in 1973. The drug diclofenac is available as sodium or potassium salts.
Use of Diclofenac:
Diclofenac is used for
pain, inflammatory diseases, dysmenorrhea, or painful menstruation. Inflammatory
diseases include arthritis, rheumatoid arthritis, osteoarthritis, polymyositis,
dermatomyositis, ankylosing spondylitis, gout, etc.
It is also used in cases
of kidney stones or gallstones, migraine pain, etc. Diclofenac is also used to
relieve post-operative or traumatic mild to moderate pain. Diclofenac is also
available as an ointment that is used topically for strain or traumatic or
inflammatory pain. [6] It is used in cancer pain.
Redirection of Diclofenac:
Hypersensitivity to
diclofenac.
The third trimester of
pregnancy.
Stomach and peptic
ulcer.
Inflammatory bowel diseases such as Ulcerative colitis, Crohn's disease, Liver and
kidney disease.
Side Effects of Diclofenac:
Diclofenac increases the
risk of a heart attack. FDA Medical Officer David Graham reviews that diclofenac
increases the risk of myocardial infarction. It can also cause peptic ulcers and
liver damage. Diclofenac can damage the kidneys by reducing prostaglandin
synthesis in the kidneys. Recent studies have shown that regular use of
diclofenac increases the risk of stroke.
Regular use of diclofenac and other drugs in this group, such as aspirin, can cause temporary infertility. Depression, anxiety, restlessness, nightmares, etc. can cause mental disorders. It can cause worm antibody hemolytic anemia.
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Diclofenac: Use, Redirection and Side Effects
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